Introduction: An increased prevalence of candidiasis is well documented and also Candida albicans has been shown to play an important role in oral candidiasis. The study aimed to compare the antifungal activity of extracts of green tea, ginger, a mixture of green tea and ginger against laboratory (ATCC 90028) and clinical strains of Candida albicans². The study aimed to compare the antifungal activity of extracts of green tea, ginger, a mixture of green tea and ginger against laboratory (ATCC 90028) and clinical strains of Candida albicans. Materials and methods: Green tea leaves and ginger were collected and sun-dried for 3 days, and ground to powder. The alcoholic extract was prepared using a Soxhlet apparatus. The concentrated extract was used to prepare serial dilutions into which incubated heat Polymethylmethacrylate (PMMA) specimens were immersed, which was used in testing antimicrobial efficacy. The study was carried out using well diffusion technique. The zone of inhibition was measured for each sample. Results: Laboratory strains have shown about 16 to 18 mm of a zone of inhibition at a concentration of 100 mg/mL. For clinical strains, Ketoconazole and denture cleansing tablet have shown considerable inhibition as compared to green tea and ginger extract. Conclusion: Indiscriminate use of such plant material by either incorporation, immersion or mouthwash is not going to reduce Candidal activity. There is a need to estimate the specific biological activity of medicinal plants for better application in medical field.