Oral submucous fibrosis (OSMF) is a crippling disorder which is confined almost exclusively to the Indian subcontinent. The available epediomological data showed clear cut geographical and ethnic predisposition, which suggested that certain customs/ habits prevalent among the population groups in the south-east asia might be etiological factors. Despite its association with a significantly increased risk of cancer, the etiology is still not clear. More research is needed to elucidate the problem.
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