Journal of Contemporary Dentistry

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VOLUME 8 , ISSUE 3 ( September-December, 2018 ) > List of Articles


Comparison of the Effect of Various Tobacco Habits on the Lipid Profile in a Population of Middle-aged Individuals: A Cross-sectional Analytical Study

Deepa Das, Anuja Shinge, Bhakti Soman

Keywords : Coronary artery disease, Lipid profile, Tobacco chewing, Tobacco smoking

Citation Information : Das D, Shinge A, Soman B. Comparison of the Effect of Various Tobacco Habits on the Lipid Profile in a Population of Middle-aged Individuals: A Cross-sectional Analytical Study. J Contemp Dent 2018; 8 (3):115-119.

DOI: 10.5005/jp-journals-10031-1234

License: CC BY-ND 3.0

Published Online: 01-12-2017

Copyright Statement:  Copyright © 2018; The Author(s).


Background: There is now a worldwide epidemic of cardiovascular disease, atherosclerosis being the most common. Mostly the atherosclerotic-related diseases are acquired diseases. Tobacco is the most critical risk factor for atherosclerotic diseases which can be controlled and preventable. In this context, the aim of this study was to evaluate the consequences of chronic use of tobacco on the lipid profile of the middle-aged population. Aim: Aim of the study was to evaluate the impact of various tobacco habits on the serum lipid profile. Materials and methods: Patients who attended the outpatient department (OPD) of Oral Medicine Diagnosis and Radiology (OMDR), screened randomly for habits of tobacco smoking and chewing, 45 patients were selected who had a habit of smoking and/or chewing tobacco, as a study group and 15 patients with no habits were chosen as the control group. Detailed information was taken regarding the frequency, duration, content of the form of tobacco they used. The patients were subjected to estimation of lipid profile. The values were recorded and statistically analyzed. Comparison of lipid profile and atherosclerotic index between tobacco smokers, tobacco chewers and nonsmokers/chewers were done using appropriate statistical analysis test. A p-value < 0.05 was considered to be statistically significant. Results: There was a significant increase in the total cholesterol (TC), low-density lipoprotein (LDL) and atherosclerotic index (AI) levels were observed in the tobacco users when we compared with nontobacco users. However, high-density lipoproteins (HDL) which is good cholesterol has a high level in nonusers compared to tobacco users Conclusion: Increased levels of TC and LDL are the risk factors in the developing coronary heart disease. As tobacco is the known risk factor for atherosclerosis, extensive awareness is essential and can save the lives of many.

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  1. Haragopal R, Aruna BM. Effects of Tobacco Chewing on Serum Lipid Profile in South Indian Population. International Journal of Scientific Study. 2016 Jul 1;4(4):9-11.
  2. Reddy SS, Ali KS. Estimation of nicotine content in popular Indian brands of smoking and chewing tobacco products. Indian Journal of Dental Research. 2008 Apr 1;19(2):88.
  3. World Health Organization, Research for International Tobacco Control. WHO report on the global tobacco epidemic, 2008: the MPOWER package. World Health Organization; 2008 Feb 11.
  4. Ch SR. The effect of chronic tobacco smoking and chewing on the lipid profile. Journal of clinical and diagnostic research: JCDR. 2013 Jan;7(1):31.
  5. Millán J, Pintó X, Muñoz A, Zúñiga M, Rubiés-Prat J, Pallardo LF. Lipoprotein ratios: physiological significance and clinical usefulness in cardiovascular prevention. Vascular health and risk management. 2009;5:757.
  6. Devaranavadgi BB, Aski BS, Kashinath RT, Hundekari IA. Effect of cigarette smoking on blood lipids–A study in Belgaum, Northern Karnataka, India. Global Journal of Medical Research. 2012;12(6):57-60.
  7. Brischetto CS, Connor WE, Connor SL, Matarazzo JD. Plasma lipid and lipoprotein profiles of cigarette smokers from randomly selected families: enhancement of hyperlipidemia and depression of high-density lipoprotein. The American journal of cardiology. 1983 Oct 1;52(7):675-680.
  8. Gadpal RR, Deshpande KA, Waghmare MH. A Study of Lipid Profile in Tobacco Chewers and Smokers. J Contemp Med Dent. 2015;3:39-43.
  9. Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. Journal of the American college of cardiology. 2004 May 19;43(10):1731- 1737.
  10. Neki NS. Lipid profile in chronic smokers–A clinical study. Journal, Indian Academy of Clinical Medicine. 2002 Jan;3(1):51-54.
  11. Craig WY, Palomaki GE, Haddow JE. Cigarette smoking and serum lipid and lipoprotein concentrations: an analysis of published data. BMJ. 1989 Mar 25;298(6676):784-788.
  12. Adedeji OA, Etukudo MH. Lipid profile of cigarette smokers in Calabar municipality. Pakistan journal of nutrition. 2006;5(3):327-328.
  13. Nagaraj PM. Effect of Cigarette Smoking on Lipid Profile. Journal of Biomedical and Pharmaceutical Research. 2014 Jun 28;3(3).
  14. Ahmed QR, Gupta N, Goyal S, Ansari SJ. Comparative study on lipid profile in tobacco chewers and nontobacco chewers. Natl J Physiol Pharm Pharmacol. 2015 Jan 2;5(2):142-144.
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